Movement Disorders and Neuromodulation

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Movement Disorders and Neuromodulation

Movement disorders are neurological conditions affecting speed, fluency, quality, and ease of movement. Deep brain stimulation (DBS) is used to treat advanced Parkinson's disease, essential tremor, and dystonia. Possible target sites for DBS include the ventral intermediate nucleus of the thalamus, the globus pallidus internus, and the subthalamic nucleus. High-frequency DBS leads to a kind of ...

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Thisthemeissueon“CircuitsandCircuitDisorders:Approaches to Neuromodulation” is the result of a symposium held at the annual meeting of the American Neurological Association in Chicago, Illinois, on September 26, 2015, and cosponsored by JAMA Neurology and the Annals of Neurology. The speakers wereMahlonDeLong,MD,EmoryUniversity (KeynoteSpeaker), Philip Starr, MD, University of California, San F...

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Do Disorders of Movement Cause Movement Disorders and Dementia?

Neurons require long-distance microtubule-based transport systems to ferry vital cellular cargoes and signals between cell bodies and axonal or dendritic terminals. Considerable progress has been made on developing a molecular understanding of these processes and how they are integrated into normal neuronal functions. Recent work also suggests that these transport systems may fail early in the ...

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In this paper the use of PET for determining the patterns of disruption of both regional cerebral metabolism, and the pre- and post-synaptic dopaminergic systems, associated with movement disorders is reviewed. That the various akinetic-rigid syndromes result in distinctive PET findings is shown, making functional imaging valuable in their differential diagnosis. PET may also be useful for dete...

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ژورنال

عنوان ژورنال: Neurology Research International

سال: 2012

ISSN: 2090-1852,2090-1860

DOI: 10.1155/2012/309431